Welcome to the webpage for the Bio-Engineering of Advanced Mechanical Systems (BEAMS) Laboratory at UC Irvine.

The BEAMS Lab was established by Dr. Elliot Botvinick in 2007. It is part of the University of California Irvine's Departments of Surgery and Biomedical Engineering. The BEAMS group has laboratories at the Beckman Laser Institute and Clinic as well as the Edwards Lifesciences Center for Advanced Cardiovascular Technology. We are curious about intrinsic and external mechanical forces in cellular micro-environments and their effects on the behavior and molecular signaling of cells. This is a growing area of research in which we differentiate ourselves through the application of optical tweezers, engineered platforms, and by always seeking out interesting collaborative relationships.


Congratulations to our PI Dr. Elliot Botvinick, recognized as Faculty Mentor of the Month in the Biomedical Engineering Department

Congratulations to our very own Dr. Abhishek Kurup! He defended with his thesis "Spatial awareness: how cells respond and control extra cellular matrix stiffness topography". We are sad to let him go but utterly proud and eager to see what his next accomplishment will be!

Congratulations to our graduating seniors Horacio Estabridis, Kelsey Fung, Anthony Pham, and Janelle Halog. Good luck on your future endeavors!

Professor Botvinick is awarded the UCI Samueli School of Engineering "Innovator of the Year" award for the 2014-2015 academic year.

"Mr. Twisty" patent issued View Patent.

BEAMS Lab presentations at SPIE Optics + Photonics 2014 Conference:

"MicroTsunamis: a method for high-throughput screening of cellular mechanotransduction using laser microbeam generated cavitation bubbles," presented by Justin Luo

"Quantifying change in stiffness heterogeneity in 3D around cells embedded in natural ECMs over time," presented by Mark Keating

Dr. Jonathan Compton and PhD student Justin Luo publish the MicroTsunamis technology in Nature Photonics.

BEAMS Lab paper "Method measuring oxygen tension and transport within subcutaneous devices" published in the Journal of Biomedical Optics.
Authors: John Weidling, Sara Sameni, Jonathan R. T. Lakey, Elliot Botvinick