BECKMAN LASER INSTITUTE

BIO-ENGINEERING OF ADVANCED MECHANICAL SYSTEMS

BEAMS LAB 2009

RESEARCH

The BEAMS Lab focuses on the relationship between mechanical stresses on cells and their microenvironment. The use of laser tweezers is integral in evaluating and influencing the microenvironment of a cell. As such, all the projects associated with the BEAMS Lab involves the use of laser tweezers in capturing microparticles and using them as a means to assess local microenvironment forces and to induce forces onto a cell and its environment.

Browse the projects listed below to learn more about BEAMS Lab research!

 

CURRENT PROJECTS

MICRORHEOLOGY OF HYDROGELS

Using microrheology as a tool to study, and improve design of, tissue engineering constructs. Laser tracking beads are used to study the microenvironment of PEG-Fibrinogen hydrogels.

 

FLUID FLOW INDUCTION OF ENDOTHELIAL NITRIC OXIDE PRODUCTION

Using fluorescently marked cells and laser tweezers to measure stresses induced by vaterite particles on BAEC cells and measuring nitric oxide production with an NO detector.

 

MEASURING ADHESION FORCES USING OPTICAL TWEEZERS

Using optical tweezers and position senstivite diodes to assess the adhesion forces between cells or substrates to specific antibodies covalently attached to polystyrene beads.

RESEARCH

Various projects underway in the MMS Lab